Full Paper
Tomasz Kruczyński(1) , Agnieszka Łapczuk(2)🖂,
(1) Department of Chemistry and Biochemistry, Kennesaw State University, Kennesaw, 30144, GA, United States
(2) Cracow University of Technology, Faculty of Chemical Engineering and Technology, Department of Organic Chemistry and Technology, Warszawska 24, 31-155 Cracow, Poland
* Correspondence to:agnieszka.lapczuk@pk.edu.pl
pp. 223-233
Abstract
Selected nitronorbornene analogs bearing different substituents were analyzed using in silico methods to predict their biological and pharmacokinetic properties. The compounds demonstrated potential biological activity, as indicated by PASS predictions, and exhibited favorable ADME profiles based on SWISS ADME analysis. These findings highlight their promise as candidates for further experimental evaluation and potential pharmacological applications.
Selected nitronorbornene analogs bearing different substituents were analyzed using in silico methods to predict their biological and pharmacokinetic properties. The compounds demonstrated potential biological activity, as indicated by PASS predictions, and exhibited favorable ADME profiles based on SWISS ADME analysis. These findings highlight their promise as candidates for further experimental evaluation and potential pharmacological applications.Keywords: nitronorbornenes, in silico analysis, PASS prediction, ADME, pharmacokinetics, biological activity
First published: 30.09.2025
