2025 vol 4 issue 3
Communication
Karolina Zawadzińska-Wrochniak 1 *, Gajendra Kumar Gaurav 2, Oleg M. Demchuk 3
1 Radom Scientific Society, Rynek 15, 26-600 Radom, Poland
2 Sustainable Process Integration Laboratory – SPIL, NETME Centre, Faculty of Mechanical Engineering, Brno University of Technology – VUT Brno, Technická 2896/2, 616 69 Brno, Czech Republic
3 Laboratory of Modern Chemical Synthesis and Technology of Pharmaceutically Active Compounds, Centre for Interdisciplinary Research, Faculty of Science and Health, The John Paul II Catholic University of Lublin, Lublin, Poland
* Correspondence to: karolina.zawadzinska@biprotech.com
pp. 202-208
DOI: 10.58332/scirad2025v4i3a02
PDF
Abstract
The possible protocols for the effective preparation of the individual (E)-3,3,3-tribromo-1-nitroprop-1-ene were examined. It was found that, some strategies dedicated for the preparation of the (E)-3,3,3-trichloro-1-nitroprop-1-ene and (E)-3,3,3-trifluoro-1-nitroprop-1-ene, were not adequate for the obtaining of the title compound. Only diacylation process catalyzed by the inorganic bases, offer the possibility of the preparation of the nitroalkene. Its isolation and purification was also optimized.
Keywords
nitroalkenes, (E)-3,3,3-tribromo-1-nitroprop-1-ene, deacylation
First published: 11.09.2025
