Full paper
Gaflin Shelty 1 *, Sumitha Celin, Allen Gnana Raj
1 Department of Chemistry and Research Centre, Scott Christian College (Autonomous) Nagercoil, Affiliated to Manonmaniam Sundaranar University, Tamil Nādu, India
* Correspondence to: sumithaezhil77@gmail.com
pp. 29-42
Abstract
Ruthenium polypyridyl complexes have garnered attention due to their promising coordination chemistry and potential applications in biological and photophysical research. This study investigates the synthesis and binding properties of [Ru(NN)3]2+ complexes (where NN= bpy,dmbpy) with DNA models like chicken liver DNA. Using UV – Visible and emission spectroscopy, significant bathochromic shifts were observed, indicating strong interactions and possible intercalative binding. The results highlight the unique affinity and photophysical behavior of Ruthenium polypyridyl complexes, contributing to a deeper understanding of their potential probes as therapeutic agents. The research opens avenues forfuture explorations in medical and agricultural chemistry.
Ruthenium polypyridyl complexes have garnered attention due to their promising coordination chemistry and potential applications in biological and photophysical research. This study investigates the synthesis and binding properties of [Ru(NN)3]2+ complexes (where NN= bpy,dmbpy) with DNA models like chicken liver DNA. Using UV – Visible and emission spectroscopy, significant bathochromic shifts were observed, indicating strong interactions and possible intercalative binding. The results highlight the unique affinity and photophysical behavior of Ruthenium polypyridyl complexes, contributing to a deeper understanding of their potential probes as therapeutic agents. The research opens avenues forfuture explorations in medical and agricultural chemistry.Keywords
chicken liver DNA, Ruthenium complexes, emission, Benesi-Hildebrand plot, binding constant
chicken liver DNA, Ruthenium complexes, emission, Benesi-Hildebrand plot, binding constant
First published: 13.02.2025
